Astrazeneca AB jobb

Are you an experienced Statistical Programming professional with deep knowledge of clinical drug development? Would you like to use your technical expertise to provide strategic programming leadership and help shape the delivery of clinical development programmes? Join us at AstraZeneca CVRM (Cardiovascular Renal Metabolism) Biometrics to impact a wide range of engaging projects striving to make a difference for millions of patients. Our Biometrics team consists of Statisticians, Programmers, Information and Data Scientists. We drive and contribute to optimized clinical drug development programs and access to information and scientific knowledge management. We are now offering an exciting opportunity for a dedicated and highly motivated individual to join us as Statistical Programming, Associate Director, providing strategic programming leadership within CVRM Biometrics and collaborating with global product development teams. This role is primarily focused on strategic and technical leadership, planning and project management rather than hands-on statistical programming. You will draw on your technical programming expertise to provide direction, oversee delivery and support high-quality decision-making. This role will be placed at AstraZeneca's dynamic R&D strategic site in Gothenburg (Sweden), where you will work in an international environment at the forefront of clinical development. Accountabilities: As a Statistical Programming, Associate Director, you are accountable for quality, timely and efficient delivery of project programming work and information management. This position requires profound programming experience and excellent industry knowledge to provide strategic and technical leadership across programming activities, including planning and project management. This is a strategic leadership role with project and technical focus where you will provide subject matter expertise within the statistical programming discipline. You will oversee the delivery of data according to industry standards, and high-quality statistical analyses and reporting deliverables, as well as planning and execution of submission strategies. You will act as a specialist within cross-functional teams to drive continuous improvement, innovation, and automation solutions. Essential Skills/Experience: Degree in Mathematics (e.g., Applied Math, Engineering, etc.), Statistics, Computer Science, Life Science, or equivalent experience Advanced knowledge of the clinical development process and industry standards Demonstrated programming leadership capability, with the ability to provide strategic and technical direction, develop teams and individuals, and lead them towards a common goal without formal line management responsibility Demonstrated influencing, planning and organizational skills Ability to provide input to functional strategies Expertise in risk management in complex or novel situations Strong technical experience in SAS and CDISC standards, together with current knowledge and awareness of regulatory requirements relevant to Statistical Programming Desirable Skills/Experience: Broad experience, ideally across multiple therapeutic areas and/or beyond Statistical Programming Experience in regulatory submissions and regulatory interactions Demonstrated experience in designing and implementing business processes Willingness and ability to travel At AstraZeneca, we believe in the potential of our people, and you'll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us. In this role, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives and join us on an exciting journey to pioneer the future of healthcare. This role is an office-based role with some degree of flexibility. Our vibrant office sites provide a diverse and collaborative work environment, where interactions lead to ideas and innovations, giving you and others the perfect opportunity to learn, grow and develop careers. Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have a seat available, and we hope it's yours. Apply today! Welcome with your application no later than November 18th, 2026.

Are you a passionate individual with expertise in mathematical modelling and pharmacokinetics/pharmacodynamics (PK/PD)? Do you want to apply quantitative approaches to help shape the development of future treatments for cardiovascular, renal and metabolic diseases? If so, we invite you to join our Modelling & Simulation team within the Early Cardiovascular, Renal and Metabolism (CVRM) therapeutic area at AstraZeneca. This position is based at our dynamic R&D site in Gothenburg, Sweden. Accountabilities: As a Modelling and Simulation PK/PD expert, you will play a key role in shaping project strategies and driving critical decisions across our drug discovery portfolio. You will actively contribute to drug project teams, providing quantitative insights to inform target and molecule selection, dosing strategies, and translational development decisions. You will design and oversee the execution of complex studies in preclinical disease models, applying advanced mathematical modelling approaches to deliver impactful PK/PD and translational insights. Your expertise will enable you to synthesize data from multiple sources, predict human pharmacokinetics and pharmacodynamics, and influence the definition of efficacious exposure and dosing regimens. In this role, you will present and defend your quantitative assessments and recommendations to internal governance and senior stakeholders, shaping critical decisions at the highest levels. You will also provide scientific leadership by initiating and leading strategic DMPK and PK/PD innovation projects, fostering collaboration across disciplines, and representing AstraZeneca's modelling expertise both internally and within the broader scientific community. Essential Skills/Experience: PhD in pharmacokinetics, pharmacology, mathematics, or related field, with a focus on model-based PK/PD approaches. Industry or academic experience in exposure-response modelling such as PK/PD, NLME, PBPK and/or QSP, with hands-on experience using relevant modelling and programming tools (e.g., Phoenix, R, MATLAB, Python, Monolix, NONMEM) Demonstrated ability to integrate complex data, apply quantitative reasoning, and translate modelling results into recommendations that inform project decisions Demonstrated scientific leadership and a strong track record of scientific contributions in a relevant area Experience applying AI and machine learning to quantitative research workflows, for example in data curation, PK/PD modelling or translational modelling Excellent communication and influencing skills, with the ability to present complex quantitative results clearly to cross-functional teams and senior stakeholders Desirable Skills/Experience: Experience applying PK/PD modelling in a preclinical or translational setting Experience developing quantitative modelling strategies across multiple therapeutic modalities such as small molecules, oligonucleotides, peptides, proteins, antibodies or cell and gene therapies Experience in PBPK modelling using platforms such as Simcyp or PK-Sim At AstraZeneca, we are driven by results and use our unique blend of science and commercial knowledge to spot opportunities and drive outcomes. We are part of an expansive healthcare ecosystem that connects key players across the entire patient journey. Our patient-first approach informs every decision we make. We are committed to your development and believe that your best is better here. Join us and be part of a global team of curious, collaborative colleagues. Ready to make your mark? Apply now and be a part of our journey to redefine the future of healthcare! We welcome your application by November 17, 2026.

About the Operations IT Team:AstraZeneca Operations IT is a global IT capability supporting the Global Operations organisation. We partner with Operations Business capability areas: Pharmaceutical Technology Development, Manufacturing & Global Engineering, Quality, Sustainability, Supply Chain, Logistics and Global External Sourcing and Procurement. We operate out of Operations hubs sites including in the UK, Sweden, US, and China; and out of our Global Technology Centres in India and Mexico. What you'll do:The Director, Senior Product Owner, will use their IT expertise, bio-pharma industry trends/experience and in-depth understanding of AZ business priorities to lead the functional/capability IT/Digital strategy development, investment planning, and delivery. The role will develop and own strategic relationships with key parts of the AZ Global Quality aligned Business Process Owners identifying ways for IT to partner with the in achieving and exceeding their business objectives with regard to corporate quality assurance (PQS, QMS) and laboratory based IT processes and systems (i.e. Laboratory Information Management (LIMS), Laboratory Execution (LES), Chromatography (CDS), Environmental Monitoring (EM), Data Management (SDMS), etc…). This role will drive the development and own of the capability global strategy roadmap, sequencing, prioritization, and backlogs. The strategy will look at all aspects of IT/Digital for the capability area including the foundational and transformational solutions required to create maximum competitive advantage. The role will be accountable for the successful delivery of programs, projects, and products working with a multi-functional matrix team. Key Accountabilities will include: Be responsible for the strategic relationship with Operations Senior Leadership Team (OSLT-1) (or similar) senior leaders, Global Business Process Owners, and actively contribute to the functional leadership team (where applicable) Partner with relevant IT Teams to ensure that all IT services used by the function meet the agreed performance outcomes and drive continuous improvement initiatives as required Provide thought leadership to develop the business strategy, define the technology direction, and own the IT/Digital strategy and roadmap Drive end-to-end IT satisfaction, return on investment and TCO improvements for the functional area Main point of contact for the function to resolve and manage significant service issues/problems/incidents Partner with the business to develop clear business cases linked to business and IT outcomes Support the collation and own the prioritization of portfolio, balancing priorities and IT/Operations strategic principles and governance Lead Ideation, Innovation, and MVPs to continually improve and/or transform capability area, including working with the Data, Analytics and AI team on relevant uses cases aligned to the strategic roadmap Prioritisation of platform/product feature backlogs working closely with scaled delivery and external partners Drive the collation of information from relevant sources for analysis and trends for informed decision making, using a high degree of domain area knowledge and expertise Communicate, influence, and provide advice to relevant stakeholders to drive strategy and projects Manage and inspire a multi-functional matrix team setting clear direction for the team and removing barriers Develop strategic relationships with AZ IT Business Technology Groups (BTGs) and Centers for Enablement (C4E) colleagues, together with external partners to identify and deliver solutions that enable business objectives Leadership, planning, coordination, and delivery of projects using both traditional and agile delivery approaches Accountable for the delivery of Quality IT portfolio projects and programs including resolving issues, escalations, and identify ways to mitigate risks Essential requirements for the role: Rich experience of bio-pharma industry with strong knowledge and background in Quality Assurance, Quality Control and Laboratory systems Strong background of partnering across IT and Business stakeholders, building trustworthy relationships and establishing common objectives Strong experience in IT solution delivery to global functions in support of GxP business processes Experience of identification and implementation of innovative technology solutions A proven track record of delivering results Experience of building high value business cases & mobilising high value investments Experience of leading teams with a demonstrable track record of motivational and achievement oriented leadership Experience of managing third party suppliers and have strong network and consulting skills Strong verbal and written communication skills Strong influencing, networking and team working skills High level awareness of developments in the Information Technology marketplace Demonstrate strong relationship building skills with the ability to influence others to achieve objectives Proficiency in planning, change management and problem solving and able to resolve issues of a highly complex and strategic nature Demonstrable ability to relate and respond to business needs in an IT environment Ability to manage negotiations, expectations and solutions across complex groups Bachelor Degree or equivalent level Work policy:When we put people in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. This role is located in Södertälje, Sweden and is not available for remote work or with travel or commuting support.