Astrazeneca AB jobb

Lediga jobb hos Astrazeneca AB

Senior Engineer, Drug Product Process Engineering

Unlock the power of science and make a difference in the world of biopharmaceuticals. Are you ready to explore and innovate in our dynamic environment? Join our team at AstraZeneca's Biopharmaceuticals R&D in Gärtuna Södertälje and be part of the journey to treat, prevent, modify, and even cure some of the world's most complex diseases! At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person. AstraZeneca's BioPharmaceutical Development (BPD) department consists of scientists, engineers, mathematicians and project managers whose ambition is to transform biologic molecules into life-changing medicines. The Process Engineering and Packaging Group (PEP) Group sits in the BioPharmaceutical R&D organization. The PEP group develops clinical and commercial fill/finish processes, combination product assembly processes, and packaging for biopharmaceutical products in the AstraZeneca portfolio. This role will be based at Sweden Bio-manufacturing Center (SBC), and will serve to strengthen collaboration between development and the manufacturing operations business units. SBC, our new production unit in Södertälje, is a central part of AstraZeneca's strategy for the production, quality assurance and delivery of biological medicines. Your role We are currently seeking a highly skilled individual for Senior Engineer role, with one focused on CP Combination Assembly Design Transfer and the other on Drug Product Aseptic Fill/Finish Technology Transfer. As a key member of the PEP organization, you will play a crucial role in process development for late-stage clinical products, technology transfer to both internal and outsourced commercial manufacturing. In this role, you will provide technical and strategic leadership for the development of drug product processes and parenteral device assembly processes for late-stage programs. You will apply scientific and engineering knowledge to solve issues arising during development and execution of processes. Additionally, you will lead technology development initiatives, drive a culture of innovation, and create solid partnerships with key interfaces. Our site in Södertälje is where you'll collaborate with AstraZeneca leaders, particularly within the Global Biological Operations (Commercial Operations) organization, as well as internal/external manufacturing sites within our network. Your experience working with functions such as late-stage formulation development, device development, clinical operations, supply chain, quality, and regulatory will be essential for success in this role. Essentials * B.S., M.S., or Ph.D. in Biotechnology, Pharmacy, Mechanical Engineering, or other relevant Engineering field, Pharmaceutical Sciences, or related field with experience in the biopharmaceutical industry * Expertise in drug product/combination product process development and characterization * Strong knowledge of Quality Risk Management principles and tools * Experience in CMC aspects of biopharmaceutical development * Demonstrated ability to work in a collaborative team environment across multiple technical functions * Strong aseptic processing knowledge (Annex 1 and similar) * Process validation execution * Ability to work independently with minimal direct oversight * Ability to manage up and influence senior partners * Experience with tech transfer * Non-conformance investigation and root cause analysis * Corrective/Preventive action implementation When we put unexpected teams in the same room, we fuel bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Desirables * Experience with regulatory agency interactions or responses to regulatory queries specific to pharmaceutical development and medical devices * Strong statistical background, including SPC and DoE methodologies * Knowledge of Six Sigma * Knowledge of combination product and/or medical device development and associated design controls * Experience with various biologic modalities (mRNA, adenovirus delivery, CAR-T therapies, antibody-drug conjugates, etc.) * Experience with formulation development * Experience with lyophilization development, characterization, and scale-up Why AstraZeneca Join the team where everyone feels a personal connection to the people that we impact. From our science labs to manufacturing at scale, we are committed to delivering at the highest quality. It's inspiring and rewarding work, influencing every part of the product lifecycle to deliver life-changing medicines. To ultimately make people's lives better - from patients and their families to all of us in society. So, what's next Are you already imagining yourself joining our team - good, because we can't wait to hear from you! Welcome with your application no later than 5th May 2024.

25 april 2024
Sista ansökan:
5 maj 2024
Experienced Data Scientist in Computational Chemistry

Do you have a background in computational or theoretical chemistry or natural sciences, with a great passion for scientific computing and workflow development? Are you also enthusiastic about deriving knowledge from computational chemistry applications and data-based modelling? At AstraZeneca, we are looking for an individual like you to implement transformative computational workflows to drive predictive chemistry and the digital transformation. We are a global, science-driven biopharmaceutical business, and our innovative medicines are used by millions of patients worldwide. Our aim is to work towards a cure for some of the world's most complex diseases. Pharmaceutical Sciences at AstraZeneca delivers the therapies of the future through scientific leadership in drug delivery, design of synthetic routes, and manufacturing of Active Pharmaceutical Ingredients and drug products. In essence, we are working "from molecule to medicine" to develop medicines for our patients today and tomorrow. The Data Science and Modelling department within Pharmaceutical Sciences is developing predictive chemistry strategies along our digital transformation strategy to drive innovation and optimization of the drug development process through data, machine learning, and computational modelling driven decision making. We now have an exciting opportunity for a senior data insight analyst or associate principal data insight analyst role in scientific workflow development, depending on your background and experience in one of our data science teams based in Gothenburg, Sweden and Macclesfield, United Kingdom. The role could be placed either in Gothenburg or Macclesfield. Accountabilities: In this role, you will engage with key internal and external stakeholders to identify and validate impactful solutions. You will provide scientific leadership and drive innovation. You will be at the forefront of the digital transformation within AstraZeneca, turning ideas into life-changing medicines. Typical responsibilities in this role * Develop and assess computational chemistry and AI-driven predictive models and workflows for their application in drug development. * Critical benchmark, validate, compare, and update state-of-the-art computational chemistry workflow solutions. * Work collaboratively to link and co-develop database and dashboard solution for computational results used in drug project development. * Guide IT partners in developing web-based software application interfaces. * Represent the DS&M team in IT relations and developments. Essential Skills/Experience: * PhD in computational or theoretical chemistry/physics. For the associate principal data insight analyst role, we expect you to have +5 year post-PhD experience * Understanding of chemical reactivity, catalysis, and/or crystallization * Excellent knowledge of cheminformatics packages such as RDkit * Excellent knowledge of Python programming * Proficiency in Github and version handling Desirable Skills/Experience: * Good knowledge in statistics and machine learning applications * Experience of implementing workflows on high performance compute cluster through integration of job schedulers * Good knowledge of workflow management software such as PipelinePilot, Knime, or similar * Experience from the pharmaceutical industry To be a successful candidate, you should have excellent communication skills, written and spoken, be a self-motivated person and possess a great teamwork capability. At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Are you ready to make a meaningful impact on patients' lives? Join us at AstraZeneca and be part of a dedicated Research & Development team. Apply now! Welcome with your application; CV and cover letter, no later than May 12th, 2024.

25 april 2024
Sista ansökan:
9 maj 2024
Graduate Programme Partner - secondment/fixed term

Are you ready to be at the forefront of our pioneering early talent initiatives? As our Graduate Programme Partner, you'll play a pivotal role in nurturing the next generation of scientific talent across our sites in the US (Gaithersburg), UK (Cambridge), and Sweden (Gothenburg). This thrilling 12-month fixed-term contract/secondment offers you the chance to champion our R&D graduate programs, from attracting top-tier talent to fostering their growth and development throughout their journey with us. What you'll do: Your mission will be to ensure our programs thrive and deliver exceptional results. Collaborating with a diverse network of internal and external partners, including our early talent community, placement supervisors, and university career teams, you'll be the driving force behind every stage of the program. From recruitment and onboarding to placement management and beyond, your role will be integral to the success of our graduate programs. As well as delivering the R&D graduate programme, there may be opportunities to support other early talent programme or contribute to our cross-R&D learning and development activities, depending on skills and interest. Essential Skills/Experience: - Proactive, can-do attitude with a passion for working with Early Talent - Proven experience in a collaborative environment delivering positive business results - Excellent organizational and interpersonal skills - Strong project and program management abilities - Confident communicator comfortable representing the business both internally and externally - Tech-savvy with proficiency in various tools and platforms - Confidently handle data, adept at supporting the development and reporting of metrics. - Ability to identify and drive improvements using innovative thinking - Ability to work independently while engaging with multiple stakeholders Desirable Skills/Experience: - Experience operating across business functions and geographies - Global business area experience - Background in Research and Development/Science environment - Broad understanding of the Pharma industry - Showcase knowledge of or previous experience in the Early Talent domain. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca? Join the team unlocking the power of what science can do in our Biopharmaceuticals R&D division. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. Embrace new and varied opportunities to develop and learn. This is the place to build a long-term meaningful career as we push the boundaries of science to deliver life-changing medicines. Ready to embark on an exciting journey with us? Apply now and be part of something truly extraordinary!

25 april 2024
Sista ansökan:
5 maj 2024
Postdoc Fellow

Are you interested in an industry postdoc? Do you have a recent PhD in computer science or data science? We have an exciting opportunity for someone passionate about the power of data and Artificial Intelligence (AI) as a catalyst for change. AstraZeneca Oncology R&D, collaborating with Rigshospitalet, Copenhagen University Hospital, Denmark are seeking a talented postdoctoral data scientist to develop risk assessment methodology to guide personalized treatment decision-making for blood cancer patients. This role will be based in Gothenburg Sweden. The successful candidate will collaborate with the Copenhagen University Hospital, Professor Niemann laboratory to leverage advanced analytical techniques including machine, deep learning and graph theory utilizing Danish National CLL registry and internal AstraZeneca data. At AstraZeneca, we are united by a common purpose: to push the boundaries of science to deliver life-changing medicines. Every single day, we make a difference by delivering potentially life-changing medicines to millions of people worldwide. A significant investment in state-of-the-art data science and AI is at the forefront of our drive to make hearts healthier, help people breathe easier, and ensure more people survive cancer. About the Opportunity: Moderate to severe adverse events may lead to treatment changes which may lower the quality of life and increase the economic burden related to their management. Accurate, individualized, predictive algorithms that can identify patients that will develop serious adverse events on treatment can be used to inform patient management strategies and lead to better patient outcomes. The goal for this postdoc will be to: * Work alongside technical and domain experts, including drug project teams and the burgeoning Data Science and AI community across AZ and Rigshospitalet. * Contribute to scientific strategies & provide a rationale for targeting specific patient cohorts in studies * Develop algorithms that can be implemented to improve benefit-risk for treatment based on individualized decision support * Employ a range of machine learning techniques to reveal unique patterns and actionable insight impacting research and clinical practices. * Publish cutting edge research, code and scientific discoveries in high-impact journals, meetings and repositories. Minimum Requirements * A PhD in a quantitative discipline (Computer Science, Data Sciences, Mathematics, Physics, Computational Statistics or similar) * Excellent communication and presentation skills * Expertise solving big/complex data problems with state-of-the-art analytical techniques, * particularly in machine/deep learning (preferably for biological/health data e.g., genomics) * High programming proficiency (Python and/or R) Desired Qualifications * Experience working with pre-clinical or clinical biological data * Experience contributing to the research community through re-useable code and publication Don't miss out on this opportunity! Why AstraZeneca? At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods, and bringing unexpected teams together. Come and join our journey. So what's next? Ready to bring new ideas and fresh thinking to the table? Fantastic! We have a seat available, and we hope it's yours. We are going through applications on a regular basis so please apply as soon as possible.

24 april 2024
Sista ansökan:
15 maj 2024
Clinical Supply Program Lead

At AstraZeneca, we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development. Join our Operations team as a Clinical Supply Program Lead (CSPL), a pivotal role within Global Clinical Supply Chain. As a CSPL, you will be responsible for the end-to-end clinical supply chain of a global program of products. You will have the opportunity to influence the long-term strategy of the clinical supply chain and represent R&D Supply Chain at PT&D and Global project teams. This role offers the chance to lead a multi-functional team to drive strategy and manage supply chain performance through key performance indicators. What you'll do: As a CSPL, you will be accountable for the development and performance of clinical supply chains, owning the end-to-end supply of products in the development portfolio. You will monitor the performance of the supply chain and optimize for higher volume phases of the project, balancing speed, quality, and cost with respect to the agreed level of risk. You will lead the Supply Chain Team (SCT) which is accountable for developing and maintaining the supply plan for the program. You will also be responsible for managing a significant budget for supply activities and materials for the project. Responsibilities will include: * Influencing the design phase with relevant experts to drive an optimized supply chain design with respect to quality, risk and cost for the business * Working in conjunction with the Supply Chain planner to guarantee: Balancing Short to Mid-term Supply and Demand, Inventory Management, input into D&OP Process, planning Excellence Process Requirements, SS Master Data Management * Overall endorsement of the supply plan * Maintaining appropriate information for supply activities in PLANIT in line with RBU. * Ensuring ongoing supply through transition from development sources to commercial sources of manufacture. * Managing change in demand and supply, resolve issues, escalating when appropriate. * Understanding and acting according to GxP and understanding the impact it has on supply chain activities. * Ensuring timely delivery of information to meet internal and external regulatory and legal requirements. * Working with CSSLs to resolve issues, share standard processes and continually develop competence. * Promoting supply chain practice in PT&D and interfacing functions * Being responsible for introducing innovation into the Supply chain ensuring a culture of continuous improvement. * Taking lead in motivating others within the function and communicating the Supply Chain strategies. * Taking responsibility for handling issues and making complex trade-offs with both internal and external partners. This will require well developed conceptual and analytical thinking to make complex judgements and deliver innovative solutions. * Acting as a sponsor to support and manage the implementation of supply chain change and be the 1st point of contract for Senior Stakeholders within the organizations. Essential Skills/Experience: * Minimum education BSc or equivalent in a relevant subject area * In-depth knowledge of supply chains and drug development process. * In-depth knowledge of Clinical Development processes relevant to investigational products. * Awareness of GXP Standards within a Clinical environment. * Demand management and forecasting experience. * In-depth experience of project management and influencing and leading business partner relationships. * Proficient IT skills with an ability to adapt and operate in multiple systems. * Strong influencing, negotiating, and problem-solving skills across geographical and cultural boundaries. Desirable Skills/Experience: * Working knowledge of the Clinical Trial Directive and global regulatory environment impacting the provision of investigational products. Why AstraZeneca? At AstraZeneca, we are driven by our commitment to deliver accelerated growth and to make people's lives better. We are part of an inclusive and giving community, supporting each other on our journeys. We are leading the way in delivering Lean processes that drive greater efficiency and speed. Sustainable practices are at the heart of what we do, ensuring we manage our environmental impact across all our activities and products. Join us in making an impact on society through our sustainability goals, pioneering AstraZeneca's sustainability strategy. Ready to make a difference beyond patients? Apply no later than May 8th 2024 to be a key contributor to Zero Carbon by 2025 and carbon negative across the entire value chain by 2030. Competitive salary and benefits package on offer. Opening date: April 24th, 2024 Closing date: May 8th, 2024

24 april 2024
Sista ansökan:
4 maj 2024
Enterprise Architect, R&D Patient Safety

At AstraZeneca, we are dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your ambitious spirit. We currently have a new opportunity for an Enterprise Architect (EA), you'll be working with ground breaking technology. Care to join? The marriage between our purposeful work and the use of high-tech platforms is what sets us apart. We have an ambitious goal to lead the way in digital healthcare - from exploring data and AI, to working in the cloud on new technologies. You will join a team at the forefront. It's a dynamic and challenging environment to work in - but that's why we like it. Shape your own path, with support all the way. Diverse minds that work cross-functionally and inclusively together. Be part of a team that has the backing to innovate, disrupt an industry and change lives. Accountabilities: As an Enterprise Architect, you will be accountable for the IT capability and road map (1-5 years) for patient safety within R&D. Currently Patient safety is going through transformation form inhouse tools to cloud solutions that you will need to drive. This role is pivotal in contributing to the R&D patient safety domain and ensuring it is aligned with enterprise architecture across AstraZeneca. You will also be involved app rationalization, portfolio review, and architecture framework development. As an EA, you will ensure that common architecture decisions support both business and IS strategy within a domain focus. You will provide Enterprise Design thinking & support to AZ's Enterprise in one of the below focused domains of architecture: Business, Data, Application, Infrastructure. You will participate in Architecture Assessments & Reviews either as Reviewing Architect or as a Subject Matter Expert in the review team. You will also contribute to the development of the Architecture Capability within IS, by documenting and sharing knowledge and best practices with peer Architects and developing/maturing services aligned to architecture. Essential Skills/Experience: * Relevant technical degree or equivalent * Demonstrated technical depth & experience in at least one technical or architectural domain. * Experience influencing solution direction and standard adoption through the use of architecture capability building blocks, strategies, and roadmaps * Experience developing and leading innovative business capability definition and creation activities within one or more technical or architectural domain. * Proven experience influencing change and challenging approaches/ideas. * Experience developing and managing relationships with business stakeholders & third party suppliers * Experience working within and developing policies, procedures and guidelines within a secure, quality, and compliance environment * Strong collaboration skills with good internal/external links * Strong communication, facilitation and relationship building skills * Ability to interpret and communicate technical information into business language Desirable Skills/Experience: * Demonstrate initiative, strong customer orientation, and cross-cultural working * Understanding of the pharmaceutical/healthcare industry and of competitor activity, on a particular architecture and Information Management Technology at AstraZeneca is a home for purposeful disruptors! SO, WHAT'S NEXT? Are you already imagining yourself joining our team? Good, because we'd love to hear from you! Click the link to apply no later than May 6, and we'll be in touch as soon as we can. WHERE CAN I FIND OUT MORE? Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/ Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/ Why AstraZeneca? As Architects at AstraZeneca, we connect the dots across the business to improve the agility and functionality of our processes to accelerate AstraZeneca to the next level. We are champions of our Technology ecosystem, making sure the rest of the business experiences the true benefits of our systems. Uniting diverse areas and simplifying the way we work, changing mindsets and behaviours along the way. Our reach goes beyond technology. We are a collective of technical experts, bringing deep specialism and forward thinking to resolve complex ideas. We are curious about new ways of doing things to get to better solutions. For the business and our patients. Connecting the dots is what we do everyday, we are right at the heart of AstraZeneca's exciting digital transformation journey.

23 april 2024
Sista ansökan:
7 maj 2024
Serviceingenjör - Site Steriles, Sweden Operations

Är du en problemlösare som intresseras av spännande tekniska utmaningar och som brinner för ständiga förbättringar? Då är AstraZeneca en plats för dig! På AstraZeneca Campus Södertälje möts vi i innovativa och högteknologiska miljöer för att tillverka läkemedel som förändrar liv. En vardag kantad av orubblig team-anda, stödjande ledarskap och en nyfikenhet som förflyttar gränser. Välkommen till vår värld, där hälften av alla linjechefer är kvinnor och där vi arbetar aktivt för en friskare värld: från människa till planet. Finns driv, finns möjligheter: vilken väg väljer du? SITE Steriles finns både i Snäckviken och Gärtuna, Södertälje. Inom SITE Steriles tillverkas plastampuller för inhalation och injektion med Blow Fill Seal (BFS) teknik (Snäckviken) och Nexium I.V. (Gärtuna) som är en frystorkad produkt. Vi söker en Serviceingenjör som brinner för att arbeta med underhållsfrågor och förbättringsarbete enligt TPM/LEAN. Du kommer att ha en nyckelroll i arbetet mot en störningsfri produktion, utan akuta stopp eller haverier i maskiner och utrustningar. Ditt arbete utförs i en processorienterad organisation tillsammans med övriga medarbetare inom underhåll, samt i nära samarbete med produktionen. Tillsammans bidrar vi till att skapa förutsättningar för produktionen att kunna tillverka och leverera önskade produkter i rätt tid och till rätt kvalitet. Din roll Som Serviceingenjör blir dina huvuduppgifter att arbeta med förbättringar av underhållsstrategin och våra arbetssätt inom underhåll. Du kommer att driva utvecklingen gällande teknisk tillgänglighet för maskin och utrustning. Rollen innebär planering och genomförande av motåtgärder och förbättringar för att eliminera återkommande fel, samt säkerhetsställa arbetet med att nå stabila processer i vår produktion. Du kommer att planera aktiviteter gällande förebyggande underhåll och tillståndsbaserat underhåll tillsammans med produktionen. Du kommer optimera reservdelshållningen inom specifikt område, driva samt koordinera utrustningsspecifika avvikelser. Din roll innefattar problemlösning och förbättringsarbete i specifika uppdrag och du medverkar vid SHE- och GMP-inspektioner samt andra typer av granskningar. Arbetet utförs i GMP-miljö, vilket bl.a. innebär speciella arbetssätt och miljö med hög renhet, vilket ställer höga krav på dig som individ. Arbetet bedrivs på dagtid. Du rapporterar till Gruppchef Underhåll Site Steriles. Vi förutsätter Du som söker ska ha civil- eller högskoleingenjör inom automation, maskinteknik eller motsvarande alt. gymnasial utbildning med teknisk inriktning och flera års teknisk yrkeserfarenhet från tillverkande industri eller motsvarande. God kännedom om SHE (Safety, Health och Environment) är ett måste. Du har god datorvana och kunskap om administrativa system. Vi ser att du har goda kunskaper i svenska och engelska, såväl i tal som i skrift då leverantörskontakter ingår i arbetet samt medverkan vid inspektioner. Dokumenterad erfarenhet av underhållsteknik och GMP är meriterande, likaså erfarenhet av arbete med TPM/LEAN och liknande förbättringsarbete. Framgångsfaktorer Som person är du strukturerad, självständig och har lätt för att samarbeta och kommunicera med andra. Du har god pedagogisk förmåga, god initiativförmåga och kan leda dig själv och tvärfunktionella team för att nå uppsatta mål. Är du redo att göra skillnad? Skicka då in din ansökan, så gör vi det tillsammans! Välkommen med din ansökan senast 5/5 - 2024. Intervjuer kommer att genomföras löpande under annonseringsperioden. Om du har några frågor, hör gärna av dig till rekryterande chef Leif Ottoson.

22 april 2024
Sista ansökan:
2 maj 2024
Sr IT Business Partner

Are you ready to make a meaningful impact in the world of healthcare? We are seeking a Senior IT Business Partner to develop strategic relationships within R&D and beyond, identifying ways for IT to partner with them in achieving and exceeding business objectives. This role is a unique blend of digital, data and artificial intelligence technology utilisation, supporting and finding opportunities where IT can enable and enhance the Precision Medicine and Human Biological Samples business processes via our internal platforms & ecosystem partnerships. Join us and be part of a team with the backing and investment to win! Accountabilities: As a Senior IT Business Partner aligned to Precision Medicine and Human Biological Samples R&D, you will build strong strategic relationships with complex customer groups and senior partners, developing a deep understanding of the short-term and long-term business direction. You will assess and prioritize requirements in line with IT strategy, develop and maintain the customer account plan, run a portfolio of investments, lead high-level investigations on requirements specifications and feasibility studies, and proactively see opportunities for IT to deliver innovative technology solutions to provide competitive advantage. The role will combine Pharma and AZ internal knowledge, in-depth understanding of the business areas direction and IT expertise to drive the creation of innovative solutions. We are looking to both Diagnose and Treat disease, with the job involving definition of value cases and exploring multi option delivery paths to make a meaningful difference to patients lives. Essential Skills/Experience: * Experience in customer relationship management, including identification of Knowledge of business use cases and benefits realisation * Experience/knowledge of the Precision Medicine and Human Biological Samples and Pharma IT delivery including validation and Launch, Support & maintenance * Evidence of hands on leadership, including direct delivery of objectives and/or matrix management of others to achieve challenging goals * Evidence of leading and developing innovative solutions * A proven track record of delivering results * Experience of building high value business cases (greater than +$1million USD) & mobilising high value investments * Experience of leading teams with a demonstrable track record of motivational and achievement oriented leadership * Experience of handling third party suppliers and have strong network and consulting skills * Strong verbal and written communication skills * Strong influencing, networking and team working skills * High level awareness of developments in the Information Technology marketplace * Demonstrate strong relationship building skills with the ability to influence others to achieve objectives * Proficiency in planning, change management and problem solving and able to resolve issues of a highly complex and strategic nature * Proven ability to relate and respond to business needs in an IT environment * Ability to manage negotiations, expectations and solutions across complex groups Desirable Skills/Experience: * Experience in and knowledge of bio-pharma industry * Involvement in pharma thought leadership networks and organisations * Agile development methodologies * GxP validation * Pharmaceutical background (Therapy area does not need to match to AZ's pipeline) * Building cases for new value stream creation. * Expertise in partnership ecosystem creation, new innovation model setup (people, process and technology) * Ability to work well in and across diverse global teams * Ability to partner and work in a matrix organisation When we put unexpected teams in the same room, we fuel bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and high-reaching world. Why AstraZeneca? At AstraZeneca, we dare to lead, applying our problem-solving attitude to identify and solve opportunities across the whole enterprise. Our spirit of experimentation is lived every day through our events like hackathons. We enable AstraZeneca to perform at its peak by delivering extraordinary technology and data solutions. Our work unlocks the potential of science. We optimise and redefine AstraZeneca by maximising efficiencies and finding new ways to drive productivity. From automation to data simplification. We're part of a global company that's investing in a daring digital strategy; to become a truly data-led enterprise that disrupts the entire industry. Through the use of groundbreaking technology and data, there's huge potential for what we can achieve today and in the future. Ready to make a meaningful impact? Apply now and join us in our journey to disrupt an industry and change lives! We welcome your application no later than May 3rd.

19 april 2024
Sista ansökan:
3 maj 2024
Associate Principal Scientist in Synthetic Chemistry

Are you an experienced Synthetic Organic Chemist with a passion for applying your skills in Medicinal Chemistry? Do you envision your future in drug discovery, creating and developing novel drug molecules? If so, this is an outstanding opportunity for you! At AstraZeneca, we follow the science to explore and innovate. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. Our Early Cardiovascular, Renal and Metabolism (CVRM) Medicinal Chemistry Department is a critical player in the design and discovery of drug molecules. We are proud of our heritage of successful delivery of clinical candidates to human testing, leading to new medicines for patients. Here, we work agnostically to molecular modality and have expertise in small molecules, PROTACs, peptides, oligonucleotides, and drug conjugates. We drive our pipeline and areas of scientific leadership internally and in partnership with world experts, which provides you as a scientist with the unique opportunity to stay at the forefront of science. Accountabilities: As an Associate Principal Scientist, you will be based at AstraZeneca's dynamic R&D site in Gothenburg, Sweden. Your role will be lab-based and focused on synthetic chemistry and the enablement of novel drug molecules. You will actively contribute to AstraZeneca's portfolio of drug projects using your synthesis, route planning, data generation, and data interpretation skills. There will be opportunities to further develop both your synthetic and medicinal chemistry knowledge together with the experts in the department. Essential Skills/Experience: * Ph.D. degree in Organic Chemistry/Synthetic Chemistry with relevant multi-year industry experience. * Strong synthetic chemistry knowledge: ability to plan, prioritize and perform work independently, including synthetic route design and problem-solving. * Scientific curiosity and creativity: ability to identify, develop and apply new technologies and ways of working. * Demonstrated leadership of others to solutions of complex synthetic problems. * Great awareness of recent literature as well as current developments and trends in organic synthesis. * Highly self-motivated and capable of analyzing complex data and deciding on a focused course of action. * Excellent teamwork, collaboration, networking, and communication skills. * Track record of communication of your work both to senior chemistry leaders and in scientific papers and documents. Desirable Skills/Experience: Experience of route design and scale up chemistry in an industrial setting is preferred but not essential. At AstraZeneca, we are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. Empowered to step up, we free ourselves from fear of failure to dig deep into the biology of complex diseases and make bold decisions. Are you ready to embrace new and varied opportunities to develop and learn? This is the place to build a meaningful career as we push the boundaries of science to deliver life-changing medicines. Apply now to join our team! Welcome with your application no later than May 5th, 2024 For more information about the position please contact Hiring Manager Anders Johansson, +46-31-7761000.

18 april 2024
Sista ansökan:
5 maj 2024
Senior Scientist - Histology of immune-mediated diseases

Are you an experienced scientist ready to apply your skills in a diverse and dynamic company? If you can envision providing scientific expertise in a role that can impact patients' lives - join us now! Our team is growing and we are now looking to recruit a Senior Scientist experienced in histology with a background in image analysis and ideally experience with pathological assessment of immune-mediated diseases. If you have a drive for innovation and idea generation as well as excellent laboratory skills, this is a great opportunity to join the Bioscience In Vivo Department within Early Respiratory and Immunology. The role is located at our vibrant R&D site in Gothenburg, Sweden. Respiratory & Immunology is one of AstraZeneca's main therapy areas. From a research perspective we work to understand, treat, modify and ultimately cure respiratory and autoimmune diseases such as asthma, COPD, IPF, IBD, RA and SLE. The successful candidate will join a highly motivated team that works closely together with other departments focusing on Target Translational Science, Bioscience In vitro assays and Drug Metabolism/Pharmacokinetics to support discovery projects and to drive new exciting research. Are you ready to join us? What you'll do? As a Senior Scientist you will be a vital member of the department and in various working teams to progress our respiratory and immunological drug discovery projects. You will actively take part in scientific discussions, gain input from others and be involved in multiple project meetings to present and discuss experimental plans and data. This is a partly lab-based role where you will be actively involved in experimental phase of histological analyses, with responsibility to coordinate, perform and evaluate experiments as well as drive the establishment of new techniques. Characterization and validation of target expression and subsequent evaluation of engagement of the target by drug treatment in both patient and in vivo tissue samples will be key areas of your daily work. You will independently assess and report data with a clear understanding of its reliability, interpretation of findings and draw appropriate conclusions with input from others. We are looking for a great teammate with strong background in histology and related image analysis techniques with a specific focus on autoimmune and autoinflammatory diseases, ideally complemented by some experience in pathology and pre-clinical drug discovery processes. Essential for the role * PhD in a relevant field (area of Bioscience/Immunology) ideally complemented with experience of working in a drug discovery environment * Strong experimental histology skills in performing immunohistochemistry, istochemistry, in situ hybridization (including RNAscope) with automated machines (e.g. Ventana Discovery Ultra and Leica Bond) * Experience with immune cell identification and characterization (cluster of differentiation antigens, transcription factors, cytokines, etc)" * Knowledge in histology scoring and histomorphometry * Proven knowledge and experience in image analysis platforms (e.g. Visiopharm and Halo) * Understanding of statistical methods, quality control and data reporting/archiving * Be respectful, communicate openly and show effective collaborative behavior to obtain high quality study results * Excellent written and oral communication skills, including presentation skills. You are organized and incorporate the views of others in your communication and collaboration Desirable for the role * Knowledge of immune-mediated diseases, with a specific focus on gut, skin, joint, liver and/or kidney immunity including target and mechanism knowledge and basic understanding of pharmacokinetics * Some experience in pathology * Good understanding of pharmacology, physiology and immunology * Familiarity with deep learning image analysis methods, e.g. image segmentation and classification * Practical experience with a scripting language (Phyton, R) modelling tools * Knowledge in advanced histological techniques such as spatial transcriptomics, hyperplex staining and tissue optical clearing Why AstraZeneca? At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development. What's next? If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application until May 10, 2024. Where can I find out more? Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html Life in Gothenburg: https://www.movetogothenburg.com/ Culture and atmosphere of the Gothenburg site: https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/ Relocate to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html

18 april 2024
Sista ansökan:
9 maj 2024