Forskare, farmakologi

Institutionen för farmaci vid Uppsala universitet har en interdisciplinär miljö som är central inom läkemedelsområdet. Med forskning i frontlinjen, utbildning i toppklass och omfattande samverkan med det omgivande samhället utgör vi en viktig motor i utvecklingen av det farmaceutiska området. I den här inspirerande miljön sker forskning av internationellt hög klass med stor betydelse. Bland våra centrala kompetenser är farmakokinetik-farmakodynamik, in vitro ADME modeller, avancerade in vivo-metoder, modellering och simulering, biologiska läkemedel, liksom patientrelaterade och samhälleliga aspekter på allt från individens läkemedelsanvändning till läkemedelspolitik. Våra vetenskapliga fokusområden i urval Farmakokinetik & Farmakodynamik • Farmakometri • Klinisk farmaci • Avancerad läkemedelsformulering • Molekylär galenisk farmaci • Biologiska läkemedel • Farmakoepidemiologi • Samhällsfarmaci Mer information www.farmaci.uu.se Projekt: Biomarkörer för kemoterapi-inducerad perifer neuropati Arbetsuppgifter: Projektet omfattar forskning kring biomarkörer för kemoterapiinducerad perifer neuropati (CIPN), med särskilt fokus på neurofilament light chain (NfL) i serum samt betydelsen av barriärerna i det centrala och perifera nervsystemet för utvecklingen av CIPN. De data som genereras experimentellt kommer att användas för farmakokinetisk-farmakodynamisk modellering som ett translationsverktyg för att karakterisera sambandet mellan exponering för cytostatika i plasma och i CIPN-relevanta vävnader samt biomarkörer i serum. Studien omfattar flera mikrotubulihämmande läkemedel samt antikroppsläkemedelskonjugat (antibody-drug conjugates, ADC). Kvalifikationer:  Den sökande skall ha grundexamen inom farmaceutiskt, medicinskt, teknik/naturvetenskapligt eller angränsande område. Sökande skall ha dokumenterad erfarenhet av djurstudier inom kemoterapiinducerad perifer neuropati (CIPN), läkemedelsbioanalys med UPLC-MS/MS, bioanalys av NfL samt farmakokinetisk-farmakodynamisk modellering och simulering. Vi sätter stor vikt vid personlig lämplighet samt motivation och intresse för forskning som syftar till att förbättra säkerheten vid behandling med cytostatika. Den sökande ska kunna uttrycka sig väl, både muntligt och skriftligt, på engelska. Sökande ska kunna arbeta självständigt och i grupp. Meriterande: God förståelse för barriärernas struktur och funktion i det centrala och perifera nervsystemet. Grundläggande kunskaper om farmakokinetik av antikroppsläkemedelskonjugat. Praktisk erfarenhet av analys och modellering av farmakokinetiska-farmakodynamiska data. Intresse för och god förmåga att skriva vetenskapliga texter på engelska är meriterande. Om anställningen  Anställningen är tidsbegränsad, 4 månader. Omfattningen är 100%. Tillträde 1 september 2026 eller enligt överenskommelse. Placeringsort: Uppsala Upplysningar om anställningenlämnas av: Universitetslektor Irena Loryan, [email protected] Välkommen med din ansökan senast den 12 juli 2026, UFV-PA 2026/2374. Uppsala universitet är ett brett forskningsuniversitet med stark internationell ställning. Det yttersta målet är att bedriva utbildning och forskning av högsta kvalitet och relevans för att göra skillnad i samhället. Vår viktigaste tillgång är alla 7 500 anställda och 53 000 studenter som med nyfikenhet och engagemang gör Uppsala universitet till en av landets mest spännande arbetsplatser. Läs mer om våra förmåner och hur det är att jobba inom Uppsala universitet https://uu.se/om-uu/jobba-hos-oss/ Anställningen kan komma att säkerhetsprövas. Vid säkerhetsprövning är en förutsättning för anställning att sökande blir godkänd. Vi undanber oss erbjudanden om rekryterings- och annonseringshjälp. Ansökan tas emot i Uppsala universitets rekryteringssystem. Fackliga företrädare: Saco-S - [email protected], Seko - [email protected], ST (OFR/S) - [email protected] Öppen för alla Vi fokuserar på din kompetens, inte dina övriga förutsättningar. Vi är öppna för att anpassa rollen eller arbetsplatsen efter dina behov.

Join us as a Global Study Associate Director (GSAD) in our BioPharmaceuticals Clinical Operations team at AstraZeneca's dynamic R&D site in Gothenburg (Sweden). This role is pivotal in the delivery of clinical studies, providing direction and guidance to a cross-functional study team within the Cardiovascular, Renal and Metabolism (CVRM) therapy area. As the main liaison between the study team and the Clinical Program Team (CPT), you will be accountable for the delivery of a study according to agreed timelines, budget, and quality standards. Accountabilities As a GSAD, you will lead and provide guidance to a cross-functional study team, ensuring the clinical study progresses as planned. You will be responsible for developing essential study level documents, overseeing external service providers, and ensuring all systems used at a study-level are current and accurate. You will also oversee study level performance against agreed upon plans, milestones, and key performance indicators. Additionally, you will be responsible for study budget re-forecasting and management throughout the study lifecycle. Essential Skills/Experience University degree (or equivalent), preferably in medical or biological sciences or discipline associated with clinical research Relevant clinical experience in the pharmaceutical industry, including project management experience Extensive study management experience Extensive knowledge of ICH-GCP, clinical research regulatory requirements Demonstrated solid project management skills Strong abilities in team leadership with experience from cross-functional leadership of a clinical study or part of a clinical study Excellent communication and interpersonal skills Strong strategic and critical thinking abilities Ability to manage competing priorities Desirable Skills/Experience Advanced degree, master's level education (or higher) Project management certification Proven project management experience on a global level Experience in all phases of a clinical study lifecycle At AstraZeneca, we are driven by our passion for science and our commitment to making a difference. We fuse data and technology with the latest scientific innovations to achieve breakthroughs that have never been done before. Our inclusive environment allows us to work seamlessly as one, leveraging our diverse global knowledge to create the greatest impact on disease. We are constantly advancing our scientific knowledge to shape the future of healthcare and improve patient access to life-changing medicines. If you are ready to make a significant impact on patients' lives and push the boundaries of science, apply now! We welcome your application by Aug 16th, 2026.

Help shape the future of pharmacovigilance science Use your expertise in epidemiology to promote the safer use of medicines and vaccines worldwide. UMC is looking for a Senior Epidemiologist to join our Pharmacovigilance Science section and strengthen our research into medicines safety using global safety and healthcare data. Since 1978, Uppsala Monitoring Centre (UMC) has been dedicated to developing, supporting, and expanding the field of pharmacovigilance science and practice.  As a World Health Organization (WHO) Collaborating Centre, we support work around the world to examine the potential adverse effects of medicines and vaccines and contribute to safer, more informed care of patients.  We are a diverse, international group of pharmacists, physicians, data scientists, system developers, communicators, and many other professionals motivated by a deep belief that the work we do matters. About the role As a Senior Epidemiologist, you will contribute epidemiologicalexpertiseto our research and scientific development activities. Working at the intersection of epidemiology, pharmacovigilance, and real-world data, and with VigiBase, the WHO global database of adverse event reports, as well as other healthcare databases and registries, you will design, conduct, and interpret studies that strengthen our understanding of medicine safety and support evidence-based decision-making. This is a hands-on role spanning the full research process, from study design and data management to statistical programming, analysis, and scientific reporting. Working closely with colleagues across disciplines, you will help generate evidence that advances the science and practice of pharmacovigilance. You will join an international research environment dedicated to advancing the science of pharmacovigilance and improving the safer use of medicines globally. What you will do Lead and contribute to research aimed at improving the understanding and use of VigiBase, the WHO global database of adverse event reports, other healthcare databases, and health registries. Design epidemiological studies andprovidemethodological advice on study design and analytical approaches. Write,maintain, and review analytical code for the management and analysis of complex real-world data. Support signal management activities through data extraction, analysis, interpretation, and investigation of potential safety issues. Collaborate on multidisciplinary research projects using adverse event reporting and healthcare data. Contribute scientificexpertiseto research and methodological development in pharmacovigilance. Work closely with colleagues across Research, Signal Management, and other teams throughout the organisation. Who you are You havea strong foundationin epidemiological methods and enjoy working with complex real-world data. You are equally comfortable discussing study design with colleagues and writing the code needed to implement it. You combine scientificrigourwith practical judgement and enjoy collaborating across disciplines to deliver impactful research. You thrive in a collaborative, learning-oriented environment. You take responsibility for your work and shared team outcomes, are comfortable with uncertainty and complexity, and remain focused when managing multiple priorities. You value openness, learning, and different perspectives, and contribute to an environment of trust and psychological safety. Required An MSc or higher in epidemiology, public health, biostatistics, medicine, or a closely related field. At least two years' experience conducting observational epidemiological studies using complex real-world data, preferably including Swedish register data and/or individual case safety report data. Strongexpertisein causal inference, including identifying sources of bias and applyingappropriate analyticalmethods. A demonstrated record of scientific output, such as peer-reviewed publications or technical reports. Experienceprovidingmethodological guidance on study design, execution, and interpretation. Demonstrated experience programming and conducting epidemiological analyses using R and/or SQL (or another statistical programming language). Excellent written and spoken English. Desired qualifications A PhD in epidemiology, pharmacoepidemiology, public health, biostatistics, ora relateddiscipline. Experience in pharmacovigilance, drug safety, regulatory science, or post-marketing surveillance. Experience using Git for collaborative code management. Experience collaborating with international stakeholders. Experience mentoring junior scientists or contributing to scientific capacity building. Uppsala Monitoring Centre (UMC) is an independent, self-funded, non-profit foundation established in 1978 dedicated to safer use of medicines and vaccines. Through an agreement between the Government of Sweden and the World Health Organization (WHO), UMC operates the Programme for International Drug Monitoring, supporting over 180 member countries and regions in strengthening safety surveillance, and maintains VigiBase, the WHO global database of adverse event reports. In addition, UMC provides international standards and related digital solutions for secure exchange of pharmacovigilance data, including a global medicine and vaccine terminology for identification of medicinal products. With around 200 staff, UMC advances the science of pharmacovigilance and transforms its practice through technological innovation. UMC’s working language is English. We normally apply a probationary period to new appointments. If you have any questions regarding this position please contact the responsible manager. You will find the contact details at the end of this page. UMC follows the collective agreements between the Swedish Agency for Government Employers and Saco-S and ST. Union representatives are Malin Zaar (Saco-S) and Jessica Avasol (ST), +46 (0)18-65 60 60.